The 6th international course on « Genome instability & human disease” will take place on the 19-23 May 2025 at the Institute Curie in Paris.
This course is dedicated to PhD student, postdoc and master students. It is organized around seminars given by renowned scientists at the forefront of their respective field and activities (Poster session, elevator pitch, Chairman/Chairwoman activities). All seminars are open to Curie members.
Thematic of the course
Genome instability is a hallmark of cancer cells but also a cause of genetic diseases in humans. Our understanding of the causal relationships between genome instability and the development of human diseases rely on our knowledge of the basic mechanisms of DNA and RNA metabolism, from the spatial genome organization to the chromatin landscape up to the regulation of genome expression during development or in response to genotoxic stress. The dysfunctions of these basic mechanisms related to genome metabolism underlie human diseases including cancer, aging, neurological disorders and immune deficiency.