Romain COHEN

Medical oncologist (MCU-PH)
Department of medical oncology, Saint-Antoine hospital, Paris, France

Tel: +33(0) 1 49 28 23 36
Fax: +33(0) 1 49 28 23 44
E-mail address: romain.cohen@aphp.fr
Address: Hôpital Saint-Antoine, service d’oncologie médicale
184, rue du Faubourg Saint-Antoine – 75571 PARIS Cedex 12, France
RPPS : 10101093549

Scientific Education

• 2019-2020 : Research Fellow,
  Cancer Center Statistics, Health Science Research, Mayo Clinic, Rochester MN, USA
• 2015-2018 : PhD student, « Physiology and Physiopathology » doctoral school
  Sorbonne University
  “Phenotypic and clinical characterization of metastatic colorectal cancers with microsatellite instability”
  Saint-Antoine Research Center (INSERM UMRS 938), team « Microsatellite instability and cancer”
  Supervisor: Prof. Alex Duval, Prof. Magali Svrcek
• 2013-2014 : MSc “Health Biology, Oncology”, Pharmacology et Therapeutics
  Université Paris-Sud 11
• 2012-2013 : University Degree of biostatistics
   UPMC, Paris VI

Medical Education

• 2016-2019 : Fellow in medical oncology
  Sorbonne University; Medical oncology department, Saint-Antoine hospital, AP-HP, Paris
• 2017-2018 : University Degree of pedagogy in medical education
   Sorbonne University
• 2016 : MD, thesisSupervisor: Prof. André
  “Clinical and molecular characterization of MMR-deficient metastatic colorectal cancer”

Clinical Research Activity

• 2019 : Good Clinical Practice certification
  Principal investigator of:
  • Phase 3 trial : 1 (NCT02872116)
  • Phase II trial : 3 (NCT03202758, NCT03186326, NCT03350126)
  • Prospective cohorts: 3 (NCT03259009, NCT02502656, COLOMIN2)

Main Publication

• URL: https://www.ncbi.nlm.nih.gov/myncbi/1vIAzn-4bQt5g/bibliography/public/
• Ludford K, Cohen R, Svrcek M, Foo WC, Colle R, Parc Y, Thomas JV, Morris VK, Kopetz S, Chang GJ, Overman M, Andre T. Pathological tumor response following immune checkpoint blockade for deficient mismatch repair advanced colorectal cancer. J Natl Cancer Inst. 2020 Apr 15 [Epub ahead of print]
• Delattre JF, Cohen R, Henriques J, Falcoz A, Emile JF, Fratte S, Chibaudel B, Dauba J, Dupuis O, Bécouran Y, Bibeau F, Taieb J, Vernerey D, André T, Svrcek M. Prognostic value of tumor deposits for disease-free survival in patients with stage III colon cancer: a post hoc analysis of the IDEA France phase III trial (PRODIGE-GERCOR). J Clin Oncol. 2020 [epub ahead of print]
• Cohen R, Vernerey D, Bellera C, Meurisse A, Henriques J, Paoletti X, Rousseau B, Alberts S, Aparicio T, Boukovinas I, Gill S, Goldberg R, Grothey A, Hamaguchi T, Iveson T, Kerr R, Labianca R, Lonardi S, Meyerhardt J, Paul J, Punt C, Saltz L, Saunders M, Schmoll HJ, Shah M, Sobrero A, Souglakos I, Taieb J, Takashima A, Wagner AD, Ychou M, Bonnetain F, Gourgou S, Yoshino S, Yothers G, de Gramont A, Shi Q, André Y. Guidelines for time-to-event endpoint definitions in adjuvant randomized trials for localized colon cancer patients: results of the DATECAN initiative. Eur J Cancer. 2020 Mar 12;130:63-71.
• Tougeron D, Sueur B, Zaanan A, De La Fouchardiere C, Sefrioui D, Lecomte T, Aparicio T, Guetz GD, Artru P, Hautefeuille V, Coriat R, Moulin V, Locher C, Touchefeu Y, Lecaille C, Goujon G, Ferru A, Evrard C, Chautard R, Gentilhomme L, Vernerey D, Taieb J, André T, Henriques J, Cohen R. Prognosis and Chemosensitivity of Deficient MMR Phenotype in Patients with Metastatic Colorectal Cancer: an AGEO Retrospective Multicenter Study. Int J Cancer. 2020 Jan 22;. doi: 10.1002/ijc.32879.
• de la Fouchardière C, Cohen R, Malka D, Guimbaud R, Bourien H, Lièvre A, Cacheux W, Artru P, François E, Gilabert M, Samalin-Scalzi E, Zaanan A, Hautefeuille V, Rousseau B, Senellart H, Coriat R, Flippot R, Desseigne F, Lardy-Cleaud A, Tougeron D. Characteristics of BRAFV600E Mutant, Deficient Mismatch Repair/Proficient Mismatch Repair, Metastatic Colorectal Cancer: A Multicenter Series of 287 Patients. Oncologist. 2019 Dec;24(12):e1331-e1340. doi: 10.1634/theoncologist.2018-0914
• Cohen R, Hain E, Buhard O, Guilloux A, Bardier A, Kaci R, Bertheau P, Renaud F, Bibeau F, Fléjou JF, André T, Svrcek M, Duval A. Association of primary resistance to immune checkpoint inhibitors in metastatic colorectal cancer with misdiagnosis of microsatellite instability or mismatch repair deficiency status. JAMA Oncol. 2018 [Epub ahead of print]
• Cohen R, Buhard O, Cervera P, Hain E, Dumont S, Bardier A, Bachet JB, Gornet JM, Lopez-Trabada D, Dumont S, Kaci R, Bertheau P, Renaud F, Bibeau F, Parc Y, Vernerey D, Duval A, Svrcek M, André T. Clinical and molecular characterisation of hereditary and sporadic metastatic colorectal cancers harbouring microsatellite instability/DNA mismatch repair deficiency. Eur J Cancer. 2017 Nov;86:266-274.